Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.40 |
| ▸ | SKP1 | P63208 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770697 | 0.90 | CKS1B (0.41) | GPR119CKS1BSKP1SKP2HRH3 | |
| SCHEMBL29464361 | 0.84 | CKS1B (0.39) | GPR119CKS1BSKP1SKP2HRH3 | |
| SCHEMBL19968827 | 0.84 | CKS1B (0.39) | GPR119CKS1BSKP1SKP2HRH3 | |
| SCHEMBL23770497 | 0.83 | RBP4 (0.35) | HRH3 | |
| SCHEMBL23770628 | 0.82 | CYP1A2 (0.42) | — | |
| SCHEMBL23770686 | 0.81 | RBP4 (0.35) | — | |
| SCHEMBL23770810 | 0.81 | MPL (0.32) | — | |
| SCHEMBL23770498 | 0.81 | CHRNA7 (0.31) | — | |
| SCHEMBL23770721 | 0.80 | GPBAR1 (0.33) | — | |
| SCHEMBL23770635 | 0.80 | IDH2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |