Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 6/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770725 | 0.91 | CYP1A2 (0.37) | PTPN11 | |
| SCHEMBL23770436 | 0.88 | DPP4 (0.39) | PTPN11 | |
| SCHEMBL23770673 | 0.87 | HRH4 (0.35) | — | |
| SCHEMBL23770840 | 0.86 | KDM4E (0.35) | — | |
| SCHEMBL23770608 | 0.86 | NOTUM (0.41) | TTR | |
| SCHEMBL23770779 | 0.85 | HRH3 (0.36) | CTSSTTR | |
| SCHEMBL23770433 | 0.84 | PDE10A (0.36) | — | |
| SCHEMBL23770753 | 0.84 | GRIN2B (0.36) | — | |
| SCHEMBL23770664 | 0.83 | NPY5R (0.36) | — | |
| SCHEMBL23770859 | 0.83 | CYP1A2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |