Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 12/20 | 0.39 |
| ▸ | GALR1 | P47211 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970017 | 0.86 | HCRTR1 (0.35) | CNR1MAPK10 | |
| SCHEMBL23770734 | 0.86 | HCRTR1 (0.35) | CNR1MAPK10 | |
| SCHEMBL23770661 | 0.82 | HTR3A (0.39) | CYP1A2CYP3A4TSHRALDH1A1 | |
| SCHEMBL23770664 | 0.81 | NPY5R (0.36) | GALR2GALR1CNR2KDM4EHSD17B10 | |
| SCHEMBL23770826 | 0.80 | S1PR1 (0.41) | GALR2GALR1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL23770433 | 0.80 | PDE10A (0.36) | GALR2GALR1CNR2KDM4EHSD17B10 | |
| SCHEMBL23770452 | 0.79 | PDE10A (0.34) | GALR2GALR1CNR2KDM4ETDP1 | |
| SCHEMBL23770694 | 0.79 | GALR2 (0.40) | GALR2GALR1CNR2KDM4EHSD17B10 | |
| SCHEMBL23770739 | 0.78 | CNR2 (0.38) | GALR2GALR1CNR2 | |
| SCHEMBL23770835 | 0.77 | PTPN11 (0.34) | CNR1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |