Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 12/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770871 | 0.88 | MEN1 (0.38) | PTPN11CNR1 | |
| SCHEMBL23770868 | 0.85 | PTPN11 (0.37) | PTPN11RETSCN10ACNR1 | |
| SCHEMBL23770661 | 0.84 | HTR3A (0.39) | — | |
| SCHEMBL23770499 | 0.84 | PTPN11 (0.36) | PTPN11 | |
| SCHEMBL19970017 | 0.83 | HCRTR1 (0.35) | SCN10ACNR1MAPK10 | |
| SCHEMBL23770734 | 0.83 | HCRTR1 (0.35) | SCN10ACNR1MAPK10 | |
| SCHEMBL19951418 | 0.83 | KIF18A (0.35) | PTPN11RETSCN10ACNR1MAPK10 | |
| SCHEMBL23770844 | 0.83 | PTPN11 (0.33) | PTPN11CNR1 | |
| SCHEMBL23770500 | 0.83 | RORC (0.32) | PTPN11 | |
| SCHEMBL23770884 | 0.83 | RORC (0.36) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |