Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925114 | 0.83 | SCN1A (0.35) | IRAK4 | |
| SCHEMBL29464445 | 0.83 | SCN1A (0.35) | IRAK4 | |
| SCHEMBL23770452 | 0.82 | PDE10A (0.34) | — | |
| SCHEMBL23770466 | 0.81 | CYP1A2 (0.37) | — | |
| SCHEMBL23770431 | 0.81 | GHSR (0.36) | — | |
| SCHEMBL23770770 | 0.80 | ADRB2 (0.38) | — | |
| SCHEMBL23770791 | 0.80 | PRKCQ (0.34) | — | |
| SCHEMBL23770889 | 0.79 | WDR5 (0.31) | — | |
| SCHEMBL23770640 | 0.79 | ITGB2 (0.40) | — | |
| SCHEMBL19968845 | 0.78 | NR1H2 (0.33) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |