Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770640 | 0.87 | ITGB2 (0.40) | ABL1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL23770452 | 0.86 | PDE10A (0.34) | ABL1KDM4EGAA | |
| SCHEMBL23770827 | 0.83 | — | — | |
| SCHEMBL23770791 | 0.83 | PRKCQ (0.34) | WDR5 | |
| SCHEMBL23770466 | 0.82 | CYP1A2 (0.37) | WDR5ABL1KDM4EHSD17B10 | |
| SCHEMBL23770431 | 0.82 | GHSR (0.36) | WDR5 | |
| SCHEMBL23770770 | 0.82 | ADRB2 (0.38) | WDR5ABL1 | |
| SCHEMBL23770893 | 0.79 | GPBAR1 (0.39) | KDM4EHSD17B10 | |
| SCHEMBL23770719 | 0.79 | IRAK4 (0.33) | — | |
| SCHEMBL23770436 | 0.79 | DPP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |