Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 6/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770457 | 0.92 | IL1B (0.30) | IL1BTNF | |
| SCHEMBL23770784 | 0.86 | SYK (0.38) | IL1BCTSA | |
| SCHEMBL19970087 | 0.86 | CCNT1 (0.35) | IL1BCTSA | |
| SCHEMBL23770790 | 0.85 | IL1B (0.32) | IL1BTNF | |
| SCHEMBL23770573 | 0.85 | CCNT1 (0.36) | IL1BTNF | |
| SCHEMBL19970024 | 0.84 | MAPK3 (0.38) | IL1BTNF | |
| SCHEMBL19970019 | 0.84 | MAPK3 (0.38) | IL1BTNF | |
| SCHEMBL19970021 | 0.84 | MAPK3 (0.38) | IL1BTNF | |
| SCHEMBL23770706 | 0.84 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL23770617 | 0.82 | CYP1A2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |