Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23771981 | 0.84 | ALOX5AP (0.39) | ALOX5APFEN1PTGS2 | |
| SCHEMBL19154840 | 0.74 | ALOX5AP (0.43) | ALOX5APFEN1PTGS2 | |
| SCHEMBL18897440 | 0.71 | FEN1 (0.50) | ALOX5APFEN1PTGS2 | |
| SCHEMBL22023979 | 0.69 | NFE2L2 (0.40) | — | |
| SCHEMBL26844077 | 0.68 | ALOX5AP (0.41) | ALOX5APFEN1PTGS2 | |
| SCHEMBL13310501 | 0.67 | CA2 (0.41) | ALOX5APFEN1 | |
| SCHEMBL24863996 | 0.67 | ALOX5AP (0.43) | ALOX5APFEN1PTGS2 | |
| SCHEMBL25791648 | 0.66 | FEN1 (0.53) | ALOX5APFEN1PTGS2 | |
| SCHEMBL9873091 | 0.66 | KDM4E (0.43) | PTGS2 | |
| SCHEMBL22043270 | 0.66 | TAAR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210251991-A1 | SUBSTITUTED 2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210251991-A1 | SUBSTITUTED 2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | HAVCR2, CDV3, HMBS | ALOX5AP 3409/4885FEN1 1584/4885PTGS1 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.