Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23774660 | 0.82 | ALDH1A1 (0.39) | KCNH2POLBKMT2AALDH1A1KDM4E | |
| SCHEMBL23764878 | 0.78 | ALDH1A1 (0.39) | POLBKMT2AALDH1A1HPGDCYP3A4 | |
| SCHEMBL23774663 | 0.77 | KCNH2 (0.35) | KCNH2POLBKMT2AKDM4E | |
| SCHEMBL31476377 | 0.77 | KCNH2 (0.36) | KCNH2POLBKMT2ATTR | |
| SCHEMBL23764913 | 0.75 | ALDH1A1 (0.41) | POLBKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL23764890 | 0.73 | ALDH1A1 (0.35) | KCNH2KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL23764877 | 0.73 | — | — | |
| SCHEMBL23457107 | 0.73 | ALDH1A1 (0.33) | KMT2AALDH1A1HPGDCYP3A4HIF1A | |
| SCHEMBL22085064 | 0.72 | OPRM1 (0.34) | KCNH2POLBKMT2ATSHRALDH1A1 | |
| SCHEMBL22086953 | 0.72 | KCNH2 (0.36) | KCNH2POLBKMT2ACRBNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160732-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2021-08-19 | — | — | WO | disclosed |