Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.32 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526372 | 0.83 | OPRM1 (0.37) | KCNH2HDAC6SMN1; SMN2NT5EOPRM1 | |
| SCHEMBL29720341 | 0.81 | KCNH2 (0.34) | KCNH2HDAC6SMN1; SMN2NT5EOPRM1 | |
| SCHEMBL18526377 | 0.81 | KCNH2 (0.34) | KCNH2HDAC6SMN1; SMN2NT5EOPRM1 | |
| SCHEMBL31476398 | 0.79 | GAA (0.43) | KMT2APOLBTTR | |
| SCHEMBL24942496 | 0.79 | NT5E (0.41) | KCNH2HDAC6SMN1; SMN2NT5EKMT2A | |
| SCHEMBL30112575 | 0.79 | NT5E (0.41) | KCNH2HDAC6SMN1; SMN2NT5EKMT2A | |
| SCHEMBL13435046 | 0.78 | KMT2A (0.53) | KCNH2SMN1; SMN2NT5EKMT2ATTR | |
| SCHEMBL22086953 | 0.77 | KCNH2 (0.36) | KCNH2HDAC6KMT2APOLBACHE | |
| SCHEMBL23774662 | 0.77 | KCNH2 (0.34) | KCNH2KMT2APOLBTTR | |
| SCHEMBL23291866 | 0.77 | NT5E (0.38) | KCNH2HDAC6SMN1; SMN2NT5EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | PFAS, FLI1, ARFGEF1 | KCNH2 1629/4885HDAC6 306/4885SMN1; SMN2 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.