SCHEMBL23775660

SCHEMBL23775660

CC(C)(C)OC(=O)NCCN1CCN(Cc2cccc(F)c2)CC1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.54
SUCNR1 Q9BXA5 2/20 0.51
KMT2A Q03164 1/20 0.51
SIGMAR1 Q99720 3/20 0.51
NPY2R P49146 1/20 0.51
CACNA1G O43497 1/20 0.51
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
FAAH O00519 1/20 0.49
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23775506 0.87 DRD2 (0.57) DRD2SUCNR1SIGMAR1CACNA1G
SCHEMBL23775742 0.86 DRD2 (0.58) DRD2SUCNR1SIGMAR1NPY2RCACNA1G
SCHEMBL31301273 0.86 DRD2 (0.64) DRD2SUCNR1SIGMAR1FAAH
SCHEMBL3440056 0.86 DRD2 (0.64) DRD2SUCNR1SIGMAR1FAAH
SCHEMBL23775768 0.82 DRD2 (0.57) DRD2SUCNR1KMT2ASIGMAR1FAAH
SCHEMBL34460001 0.82 DRD2 (0.57) DRD2SUCNR1KMT2ASIGMAR1FAAH
SCHEMBL23142613 0.82 FAAH (0.59) KMT2ASIGMAR1CACNA1GCYP2D6CYP2C9
SCHEMBL8536087 0.80 CYP2D6 (0.61) KMT2ANPY2RCYP2D6CYP2C9ALOX15
SCHEMBL23775681 0.80 DRD2 (0.69) DRD2SUCNR1KMT2ASIGMAR1
SCHEMBL5729170 0.80 CTSS (0.54) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3796900-B1 TRITERPENE AMINE DERIVATIVES DFH THERAPEUTICS (US) 2026-04-08 EP disclosed
US-11236122-B2 Triterpene amine derivatives DFH THERAPEUTICS (US) 2022-02-01 US disclosed
US-20210253627-A1 TRITERPENE AMINE DERIVATIVES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253627-A1 TRITERPENE AMINE DERIVATIVES BET1, PGGT1B, NFATC1 DRD2 285/4885SUCNR1 2517/4885KMT2A 3133/4885
US-11236122-B2 Triterpene amine derivatives BET1, PGGT1B, NFATC1 DRD2 285/4885SUCNR1 2517/4885KMT2A 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.