Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23778650 | 0.88 | MTNR1A (0.48) | TP53MAPTSMN1; SMN2LMNACNR1 | |
| SCHEMBL23778729 | 0.86 | CXCR2 (0.39) | TP53MAPTSMN1; SMN2LMNACXCR2 | |
| SCHEMBL23778733 | 0.83 | THRB (0.45) | TP53MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL23778725 | 0.83 | LMNA (0.45) | MAPTSMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL23778661 | 0.82 | SMN1; SMN2 (0.41) | TP53MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL23778656 | 0.82 | KDM4E (0.44) | TP53MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL23778670 | 0.82 | TP53 (0.46) | TP53MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL23778714 | 0.82 | GSK3B (0.45) | CXCR2HPGDCNR1POLB | |
| SCHEMBL23778726 | 0.80 | TYMP (0.46) | MAPTKDM4EHPGDTYMPMEN1 | |
| SCHEMBL23778736 | 0.77 | NOTUM (0.45) | MAPTSMN1; SMN2CXCR2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873890-A1 | NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF | Ahammune Biosciences Private Limited (IN) | 2021-09-08 | — | — | EP | disclosed |