SCHEMBL23778656

SCHEMBL23778656

CC(C)(C)CC(=O)NCCc1c[nH]c(-c2ccc(Cl)cc2)n1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.44
HSD17B10 Q99714 4/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
TP53 P04637 6/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
THRB P10828 2/20 0.40
MAPT P10636 2/20 0.39
TSHR P16473 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23778733 0.84 THRB (0.45) ALDH1A1HPGDTP53SMN1; SMN2THRB
SCHEMBL23778650 0.84 MTNR1A (0.48) HSD17B10TP53SMN1; SMN2MAPTTSHR
SCHEMBL23778661 0.83 SMN1; SMN2 (0.41) KDM4EHSD17B10ALDH1A1HPGDTP53
SCHEMBL23778670 0.83 TP53 (0.46) ALDH1A1TP53SMN1; SMN2THRBMAPT
SCHEMBL24088765 0.82 LMNA (0.47) KDM4EHSD17B10ALDH1A1HPGDTP53
SCHEMBL23778690 0.82 DRD2 (0.45) KDM4EALDH1A1HPGDTP53SMN1; SMN2
SCHEMBL23778677 0.82 THRB (0.41) HSD17B10ALDH1A1TP53SMN1; SMN2THRB
SCHEMBL23778698 0.82 TP53 (0.41) KDM4EHPGDTP53SMN1; SMN2MAPT
SCHEMBL23778643 0.81 MTNR1A (0.47) KDM4EHSD17B10ALDH1A1HPGDTP53
SCHEMBL23778652 0.81 MTNR1A (0.48) HSD17B10ALDH1A1HPGDTHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US claimed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP claimed
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2026-01-01 US disclosed
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US disclosed
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2021-12-09 US disclosed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF IDO1, IDO2, NFATC1 KDM4E 985/4885HSD17B10 2239/4885ALDH1A1 670/4885
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF MALT1, ADRM1, CYP11B1 KDM4E 4085/4885HSD17B10 1725/4885ALDH1A1 2523/4885
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof IDO1, IDO2, NFATC1 KDM4E 841/4885HSD17B10 2119/4885ALDH1A1 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.