Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774040 | 0.85 | USP30 (0.38) | CXCR2ALDH1A1GLATSHRTP53 | |
| SCHEMBL23536625 | 0.83 | CXCR2 (0.39) | CXCR2ALDH1A1NPC1RAB9ALPL | |
| SCHEMBL773437 | 0.78 | MEN1 (0.35) | ALDH1A1GLATSHRTP53SMN1; SMN2 | |
| SCHEMBL4158920 | 0.77 | AKR1B1 (0.46) | CXCR2LPLLIPGP4HB | |
| SCHEMBL23526249 | 0.76 | LPL (0.40) | CXCR2ALDH1A1TSHRSMN1; SMN2LPL | |
| SCHEMBL534958 | 0.75 | NPSR1 (0.39) | CXCR2LPLLIPGMEN1KMT2A | |
| SCHEMBL902458 | 0.74 | LIPG (0.49) | CXCR2ALDH1A1HTTLPLLIPG | |
| SCHEMBL13202078 | 0.74 | LPL (0.43) | CXCR2LPLLIPGP4HB | |
| SCHEMBL3078824 | 0.74 | TSHR (0.39) | CXCR2ALDH1A1TSHRHTTLPL | |
| SCHEMBL19817457 | 0.73 | CXCR2 (0.41) | CXCR2ALDH1A1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674040-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-03-18 | — | — | US | disclosed |
| EP-2688897-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | Exxon-Mobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| WO-2012134614-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20110224391-A1 | Pyridyldiamido Transition Metal Complexes, Production and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224391-A1 | Pyridyldiamido Transition Metal Complexes, Production and Use Thereof | PICALM, PARN, PCBP1 | CXCR2 3914/4885ALDH1A1 2590/4885GLA 3740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.