Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23779406 | 1.00 | HPGD (0.50) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31540 | 0.95 | HPGD (0.48) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2898103 | 0.95 | HPGD (0.48) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28002373 | 0.89 | HPGD (0.48) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16843 | 0.89 | NR1H2 (0.47) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL105348 | 0.89 | NR1H2 (0.47) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16018 | 0.89 | NR1H2 (0.47) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL25337897 | 0.87 | NR1H2 (0.46) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| Piperazine SCHEMBL28853588 | 0.86 | NR1H2 (0.45) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| Urea SCHEMBL4467391 | 0.84 | NR1H2 (0.44) | HPGDMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12286417-B2 | 1,4-diazocane compound or salt thereof | D. WESTERN THERAPEUTICS INSTITUTE, INC. (JP) | 2025-04-29 | — | — | US | disclosed |
| US-20210371396-A1 | 1,4-DIAZOCANE COMPOUND OR SALT THEREOF | D. WESTERN THERAPEUTICS INSTITUTE, INC. (JP) | 2021-12-02 | — | — | US | disclosed |
| EP-3875449-A1 | 1,4-DIAZOCANE COMPOUND OR SALT THEREOF | D. Western Therapeutics Institute, Inc. (JP) | 2021-09-08 | — | — | EP | disclosed |
| CN-113166044-A | 1, 4-diazacyclooctane compounds or salts thereof | 株式会社D.西医疗法研究所 | 2021-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12286417-B2 | 1,4-diazocane compound or salt thereof | SULT1E1, SULT1A1, SULT2A1 | HPGD 3239/4885MEN1 430/4885KMT2A 518/4885 |
| US-20210371396-A1 | 1,4-DIAZOCANE COMPOUND OR SALT THEREOF | SULT1E1, SULT1A1, SULT2A1 | HPGD 3239/4885MEN1 430/4885KMT2A 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.