Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701705 | 0.72 | KCNA5 (0.44) | MAPTSMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL28290723 | 0.70 | — | — | |
| SCHEMBL16544497 | 0.65 | UTS2R (0.41) | MAPTSMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL23982875 | 0.62 | — | — | |
| SCHEMBL28232057 | 0.60 | DNM1 (0.42) | SMN1; SMN2NPC1LMNAHTTRAB9A | |
| SCHEMBL28220432 | 0.58 | DNM1 (0.46) | SMN1; SMN2NPC1LMNAHTTRAB9A | |
| SCHEMBL4723984 | 0.57 | MAPT (0.41) | MAPTSMN1; SMN2MEN1NPC1HTT | |
| SCHEMBL16415843 | 0.57 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL26296867 | 0.56 | MAPT (0.39) | MAPTSMN1; SMN2HTT | |
| SCHEMBL16199856 | 0.56 | HCAR3 (0.49) | MAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875450-A1 | NRF2 ACTIVATOR | Biogen MA Inc. (US) | 2021-09-08 | — | — | EP | disclosed |