Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | HTR1D | P28221 | 1/20 | 0.74 |
| ▸ | HTR1B | P28222 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 1/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.74 |
| ▸ | HTR7 | P34969 | 1/20 | 0.74 |
| ▸ | CTSK | P43235 | 1/20 | 0.74 |
| ▸ | HTR6 | P50406 | 1/20 | 0.74 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.74 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.69 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.69 |
| ▸ | MC1R | Q01726 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378528 | 1.00 | MPO (0.74) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL5991724 | 1.00 | MPO (0.74) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL1249795 | 0.98 | MPO (0.77) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL735189 | 0.93 | MPO (0.79) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL29532652 | 0.93 | MPO (0.79) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| Hydrochloric Acid SCHEMBL21546034 | 0.91 | PMP22 (0.80) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL7889427 | 0.91 | HTR2A (0.69) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL7001306 | 0.91 | HTR2A (0.69) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL7004071 | 0.91 | HTR2A (0.69) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL7004146 | 0.89 | HTR2A (0.71) | MPOCYP3A4CYP1A2CYP2D6CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1751093-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110976-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129347-A1 | Cyclohexylacetic acid compounds | ACACA, HCAR2, PCCA | MPO 3385/4885CYP3A4 409/4885CYP1A2 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.