Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 12/20 | 0.34 |
| ▸ | TP53 | P04637 | 11/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215445 | 0.82 | EDNRB (0.44) | TGM2CES1MDM2TP53TDP2 | |
| SCHEMBL18215457 | 0.66 | TDP2 (0.38) | MDM2TDP2 | |
| SCHEMBL18209322 | 0.62 | HSD17B10 (0.49) | HSD17B10 | |
| SCHEMBL17580885 | 0.60 | APEX1 (0.40) | TGM2CES1MDM2TP53 | |
| SCHEMBL30556457 | 0.58 | TDP2 (0.41) | TGM2CES1TDP2 | |
| SCHEMBL23652262 | 0.58 | TGM2 (0.47) | TGM2CES1MDM2TP53TDP2 | |
| SCHEMBL18215447 | 0.58 | HSD17B10 (0.47) | TGM2CES1TDP2HSD17B10 | |
| SCHEMBL11358485 | 0.58 | HSD17B10 (0.47) | HSD17B10 | |
| SCHEMBL16267346 | 0.57 | MAOA (0.50) | TGM2CES1TP53TDP2 | |
| SCHEMBL21224167 | 0.57 | TGM2 (0.50) | TGM2CES1TP53TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3292102-B1 | ISOINDOLINONES, PROCESSES FOR THE PRODUCTION OF CHIRAL DERIVATIVES THEREOF AND USE THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2021-09-08 | — | — | EP | disclosed |