Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689398 | 0.91 | RORC (0.41) | RORCKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL16689436 | 0.85 | RORC (0.37) | RORCKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL23784651 | 0.85 | PIK3CA (0.34) | KDM4ELMNAHTTSMN1; SMN2ORAI1 | |
| SCHEMBL23784648 | 0.83 | PKM (0.35) | ORAI1 | |
| SCHEMBL16689417 | 0.83 | P2RX7 (0.45) | — | |
| SCHEMBL16688228 | 0.82 | PTGDR2 (0.32) | RORCKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL16689440 | 0.82 | P2RX7 (0.37) | — | |
| SCHEMBL16689412 | 0.82 | HTT (0.34) | RORCKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL16689416 | 0.82 | P2RX7 (0.33) | — | |
| SCHEMBL22135784 | 0.82 | RXRB (0.39) | HTTORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063144-B1 | ANTIPARASITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-08 | — | — | EP | disclosed |