Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 4/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18066769 | 0.84 | ENPP2 (0.46) | ENPP2CA2CA1TTRLPL | |
| SCHEMBL19359062 | 0.75 | ALDH1A1 (0.48) | ENPP2TTR | |
| SCHEMBL12653740 | 0.72 | CYP1A2 (0.48) | — | |
| SCHEMBL4773397 | 0.71 | NOS1 (0.39) | — | |
| SCHEMBL21404755 | 0.71 | KDM4E (0.54) | ENPP2CA2CA1TTR | |
| SCHEMBL16523221 | 0.71 | F7 (0.48) | — | |
| SCHEMBL7582475 | 0.71 | KDM4E (0.48) | — | |
| SCHEMBL16523329 | 0.71 | BACE1 (0.44) | IDO1TDO2 | |
| SCHEMBL13415 | 0.71 | BACE1 (0.44) | — | |
| SCHEMBL16738830 | 0.71 | CYP1A2 (0.57) | ENPP2CA2CA1TTRLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |