SCHEMBL23786203

SCHEMBL23786203

CC(C)c1nc(N(C)c2ccccc2)nc(N(C)c2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PTPN1 P18031 1/20 0.39
CES1 P23141 1/20 0.39
KMT2A Q03164 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
ALOX15 P16050 1/20 0.37
PDE5A O76074 2/20 0.37
MERTK Q12866 1/20 0.36
AURKA O14965 1/20 0.36
SRC P12931 1/20 0.36
GSK3B P49841 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974883 0.85 TSHR (0.53) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL10099644 0.78 ALDH1A1 (0.55) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8973771 0.76 ALDH1A1 (0.59) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17042383 0.74 MEN1 (0.51) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
Cyanate SCHEMBL28109038 0.74 TSHR (0.45) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL11364865 0.74 TSHR (0.45) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL23139603 0.74 TSHR (0.45) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8631881 0.72 TSHR (0.46) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL14869412 0.72 DHFR (0.54) TSHRCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL796429 0.72 ALDH1A1 (0.64) TSHRCYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed