SCHEMBL237866

SCHEMBL237866

C=C(C)C(=O)OCC[SiH](OCCC)OCCC

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
THRB P10828 1/20 0.50
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 3/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17002616 0.90 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5699021 0.90 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2404019 0.88 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL143882 0.87 THRB (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9757145 0.85 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL144127 0.81 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3338088 0.81 ALDH1A1 (0.50) TSHRALDH1A1
SCHEMBL21772349 0.80 TSHR (0.69) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16573 0.80
SCHEMBL30558754 0.80 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US claimed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US claimed
US-9745406-B2 Curable composition CEMEDINE CO., LTD. (JP) 2017-08-29 US disclosed
EP-2412756-B1 CURABLE COMPOSITION CEMEDINE CO LTD (JP) 2016-12-21 EP disclosed
EP-2412756-A1 CURABLE COMPOSITION CEMEDINE CO., LTD. (JP) 2012-02-01 EP disclosed
US-20120004371-A1 CURABLE COMPOSITION CEMEDINE CO., LTD. (JP) 2012-01-05 US disclosed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP disclosed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO disclosed