SCHEMBL143882

SCHEMBL143882

C=C(C)C(=O)OCC[SiH](OCC)OCC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.56
TSHR P16473 5/20 0.50
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 5/20 0.37
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757145 0.91 TSHR (0.54) THRBTSHRPOLBAPEX1HTT
SCHEMBL139125 0.89 TSHR (0.56) THRBTSHRPOLBAPEX1HTT
SCHEMBL98029 0.88 TSHR (0.59) THRBTSHRPOLBAPEX1HTT
SCHEMBL237866 0.87 TSHR (0.53) THRBTSHRPOLBAPEX1HTT
SCHEMBL19409171 0.86 TSHR (0.62) THRBTSHRPOLBAPEX1HTT
SCHEMBL16286969 0.86 TSHR (0.62) THRBTSHRPOLBAPEX1HTT
SCHEMBL19409198 0.86 TSHR (0.62) THRBTSHRPOLBAPEX1HTT
SCHEMBL29432640 0.86 TSHR (0.62) THRBTSHRPOLBAPEX1HTT
SCHEMBL5699021 0.84 TSHR (0.59) THRBTSHRPOLBAPEX1HTT
SCHEMBL28577746 0.84 THRB (0.55) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
WO-2024180279-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF PIBOND OY (FI) 2024-09-06 WO claimed
US-11975125-B2 Medical devices MICROVENTION, INC. (US) 2024-05-07 US claimed
EP-3860669-B1 MEDICAL DEVICES MICROVENTION INC (US) 2024-04-03 EP claimed
US-20230330309-A1 MEDICAL DEVICES MICROVENTION, INC. 2023-10-19 US claimed
EP-4223409-A1 LITHIUM ION ADSORBENTS Conductive Energy Inc. (CA) 2023-08-09 EP claimed
US-20230241581-A1 LITHIUM ION ADSORBENTS CONDUCTIVE ENERGY INC. (CA) 2023-08-03 US claimed
US-11590267-B2 Medical devices MICROVENTION, INC. (US) 2023-02-28 US claimed
US-20220227954-A1 POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE OAKTREE FUND ADMINISTRATION, LLC 2022-07-21 US claimed
EP-1735369-B1 FAST CURING POLYDIORGANOSILOXANES HENKEL AG & CO KGAA (DE) 2008-12-03 EP claimed
WO-2007145996-A9 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING (US) 2008-02-14 WO claimed
WO-2007145996-A2 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING CORPORATION (US) 2007-12-21 WO claimed
EP-1735369-A1 FAST CURING POLYDIORGANOSILOXANES Henkel Kommanditgesellschaft auf Aktien (DE) 2006-12-27 EP claimed
US-20060257673-A1 Laminates, their production and use CELANESE EMULSIONS GMBH (DE) 2006-11-16 US claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
WO-2005100446-A1 FAST CURING POLYDIORGANOSILOXANES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-10-27 WO claimed
US-20050234208-A1 Fast curing polydiorganosiloxanes HENKEL AG & CO. KGAA (DE) 2005-10-20 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 THRB 4533/4885TSHR 4650/4885POLB 2487/4885
US-20260118766-A1 Silicon containing coating compositions and uses thereof ITGA8, SMCHD1, GCN1 THRB 477/4885TSHR 957/4885POLB 2716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.