Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21612219 | 0.73 | BCL2 (0.34) | BCL2ALDH1A1ABCB1KLK5CA2 | |
| SCHEMBL21612220 | 0.73 | BCL2 (0.34) | BCL2ALDH1A1ABCB1KLK5CA2 | |
| SCHEMBL21612217 | 0.73 | PTPN1 (0.35) | BCL2PPARGPPARA | |
| SCHEMBL21612213 | 0.70 | KMT2A (0.42) | ALDH1A1TSHRGAAL3MBTL1MMP13 | |
| SCHEMBL13337480 | 0.69 | SYK (0.58) | ALDH1A1TSHRKLK5LMNAMAPT | |
| SCHEMBL13244981 | 0.69 | SYK (0.58) | ALDH1A1TSHRKLK5LMNAMAPT | |
| SCHEMBL28459748 | 0.69 | KLK5 (0.36) | TSHRKLK5ATMPPARGPPARA | |
| SCHEMBL21615437 | 0.67 | CA1 (0.46) | GAAMMP13KDM4ECA1HPGD | |
| SCHEMBL24234472 | 0.67 | SYK (0.49) | ALDH1A1L3MBTL1KLK5MAPTATM | |
| SCHEMBL21612226 | 0.67 | CTSK (0.43) | ALDH1A1KLK5MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275499-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Metrion Biosciences Limited (GB) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275499-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | STS, SQOR, SULT2A1 | BCL2 1525/4885ALDH1A1 263/4885TSHR 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.