Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 6/20 | 0.47 |
| ▸ | CTRC | Q99895 | 2/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787551 | 0.88 | PHLPP2 (0.54) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787582 | 0.86 | ENPP2 (0.42) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787642 | 0.84 | PHLPP2 (0.49) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787643 | 0.84 | PRMT3 (0.48) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL14542974 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787794 | 0.83 | PHLPP2 (0.52) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787693 | 0.83 | PHLPP2 (0.52) | PRMT3EP300PRMT6PRMT1PHLPP2 | |
| SCHEMBL23787590 | 0.82 | CYP1A2 (0.49) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787691 | 0.82 | CYP1A2 (0.49) | CYP1A2CYP2C9MAPK1DNASE1L3MPL | |
| SCHEMBL23787793 | 0.81 | ENPP2 (0.56) | CYP1A2CYP2C9MAPK1DNASE1L3MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | ACIBADEM MEHMET ALI AYDINLAR UNIVERSITESI (TR) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | POLG, POLB, POLA1 | CYP1A2 4524/4885CYP2C9 4465/4885MAPK1 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.