Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788474 | 0.90 | IRAK4 (0.32) | IRAK4 | |
| SCHEMBL23788611 | 0.86 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL23788638 | 0.79 | — | — | |
| SCHEMBL23788629 | 0.77 | LTB4R (0.32) | — | |
| SCHEMBL23788643 | 0.76 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL23788339 | 0.76 | REN (0.33) | — | |
| SCHEMBL23788330 | 0.76 | LTB4R (0.32) | — | |
| SCHEMBL23788557 | 0.75 | — | — | |
| SCHEMBL23788321 | 0.75 | SRD5A1 (0.38) | — | |
| SCHEMBL23778075 | 0.74 | MT-ND4 (0.35) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720857-B1 | 2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B | GALAPAGOS NV (BE) | 2021-09-08 | — | — | EP | disclosed |