Sugi Predict

Sugi Predict / Compounds / SCHEMBL237888

SCHEMBL237888

SCHEMBL237888

CCCCc1ccc(OC(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 1/20 0.50
▸ METAP2 P50579 1/20 0.43
▸ RARB P10826 1/20 0.43
▸ PPARG P37231 1/20 0.43
▸ PPARA Q07869 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ THRA P10827 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ TRPV1 Q8NER1 1/20 0.42
▸ PTGDR2 Q9Y5Y4 1/20 0.42
▸ BRS3 P32247 1/20 0.41
▸ MAPK8 P45983 1/20 0.41
▸ DHODH Q02127 1/20 0.41
▸ HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235802 0.96 PPARA (0.48) PSMB5RARBPPARGPPARAALDH1A1
SCHEMBL237711 0.95 PPARA (0.50) RARBPPARGPPARAALDH1A1
SCHEMBL237036 0.95 PPARA (0.50) RARBPPARGPPARAALDH1A1
SCHEMBL238573 0.92 GABRA1 (0.44) PSMB5METAP2ALDH1A1PTGDR2
SCHEMBL27809611 0.85 PTGDR2 (0.50) PPARGPPARAALDH1A1HPGDPTGDR2
SCHEMBL237890 0.84 RARB (0.51) RARBALDH1A1HPGDHSD17B10TRPV1
SCHEMBL235804 0.81 RARB (0.52) RARBPPARAALDH1A1THRBHSD11B1
SCHEMBL5194907 0.80 PPARA (0.54) PPARAHPGD
SCHEMBL237038 0.80 RARB (0.54) RARBPPARGPPARAALDH1A1THRA
SCHEMBL237713 0.80 RARB (0.54) RARBPPARGPPARAALDH1A1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114650915-B Layer structure with modified structure and production thereof 科思创德国股份有限公司 2024-05-31 — — CN disclosed
CN-117203063-A Method for locally coloring plastic parts using solid dyes in a color carrier layer 科思创德国股份有限公司 2023-12-08 — — CN disclosed
CN-111542565-B Plastic film with reduced UV activity 科思创德国股份有限公司 2023-08-22 — — CN disclosed
CN-114746488-A Films with special properties 科思创知识产权两合公司 2022-07-12 — — CN disclosed
CN-114650915-A Layer structure with modified structure and production thereof 科思创知识产权两合公司 2022-06-21 — — CN disclosed
CN-108778766-B Method for partially dyeing plastic parts 科思创德国股份有限公司 2021-12-31 — — CN disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 — — US disclosed
EP-3707198-B1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO DEUTSCHLAND AG (DE) 2021-10-27 — — EP disclosed
CN-108290820-B Method for recovering aromatic alcohol from melt polymerization and system for recovering same 沙特基础工业全球技术有限公司 2021-10-01 — — CN disclosed
CN-113242795-A Plastic film with high opacity and low transparency for identification documents with transparent window 科思创知识产权两合公司 2021-08-10 — — CN disclosed
US-20110206568-A1 PROCESS FOR THE PREPARATION OF DIARYL CARBONATES OR ARYLALKYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2011-08-25 — — US disclosed
US-8003817-B2 Process for the preparation of diaryl carbonates or arylalkyl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2011-08-23 — — US disclosed
US-7814626-B2 Process for the preparation of polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2010-10-19 — — US disclosed
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-03-19 — — US disclosed
US-20080319156-A1 Process For The Preparation Of Polycarbonate By The Melt Transesterification Process BAYER MATERIALSCIENCE AG (DE) 2008-12-25 — — US disclosed
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates BAYER MATERIALSCIENCE AG (DE) 2008-11-27 — — US disclosed
US-7250483-B2 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2007-07-31 — — US disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 — — US disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 — — US disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates HDHD5, ALKBH3, AHR PSMB5 4474/4885METAP2 4645/4885RARB 4514/4885
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES DHCR7, ADH1C, AKR1C4 PSMB5 4330/4885METAP2 4322/4885RARB 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.