SCHEMBL238573

SCHEMBL238573

CCCc1ccc(OC(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.44
GABRB2 P47870 4/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
PTGDR2 Q9Y5Y4 6/20 0.43
ALOX5 P09917 1/20 0.43
METAP2 P50579 1/20 0.41
BACE1 P56817 1/20 0.41
PTPN1 P18031 1/20 0.41
PSMB5 P28074 1/20 0.40
NCEH1 Q6PIU2 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237888 0.92 PSMB5 (0.50) PTGDR2METAP2PSMB5ALDH1A1
SCHEMBL235802 0.90 PPARA (0.48) PSMB5ALDH1A1
SCHEMBL237036 0.89 PPARA (0.50) ALDH1A1
SCHEMBL237711 0.89 PPARA (0.50) ALDH1A1
SCHEMBL27809611 0.88 PTGDR2 (0.50) PTGDR2BACE1NPC1ALDH1A1RAB9A
SCHEMBL238575 0.84 SLC13A5 (0.48) ALDH1A1
SCHEMBL21462963 0.79 GABRA1 (0.40) GABRA1GABRB2CNR1CNR2PTGDR2
SCHEMBL5192971 0.78 GAA (0.49) CNR1CNR2
SCHEMBL9509918 0.77 METAP2 (0.53) CNR1CNR2METAP2PTPN1
SCHEMBL122492 0.76 PTGDR2 (0.65) PTGDR2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114650915-B Layer structure with modified structure and production thereof 科思创德国股份有限公司 2024-05-31 CN disclosed
CN-117203063-A Method for locally coloring plastic parts using solid dyes in a color carrier layer 科思创德国股份有限公司 2023-12-08 CN disclosed
CN-111542565-B Plastic film with reduced UV activity 科思创德国股份有限公司 2023-08-22 CN disclosed
CN-114746488-A Films with special properties 科思创知识产权两合公司 2022-07-12 CN disclosed
CN-114650915-A Layer structure with modified structure and production thereof 科思创知识产权两合公司 2022-06-21 CN disclosed
CN-108778766-B Method for partially dyeing plastic parts 科思创德国股份有限公司 2021-12-31 CN disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 US disclosed
EP-3707198-B1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO DEUTSCHLAND AG (DE) 2021-10-27 EP disclosed
CN-113242795-A Plastic film with high opacity and low transparency for identification documents with transparent window 科思创知识产权两合公司 2021-08-10 CN disclosed
CN-113056369-A Method for producing a laminate comprising electronic components and/or functional units 科思创知识产权两合公司 2021-06-29 CN disclosed
US-20110206568-A1 PROCESS FOR THE PREPARATION OF DIARYL CARBONATES OR ARYLALKYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2011-08-25 US disclosed
US-8003817-B2 Process for the preparation of diaryl carbonates or arylalkyl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2011-08-23 US disclosed
US-7814626-B2 Process for the preparation of polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2010-10-19 US disclosed
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-03-19 US disclosed
US-20080319156-A1 Process For The Preparation Of Polycarbonate By The Melt Transesterification Process BAYER MATERIALSCIENCE AG (DE) 2008-12-25 US disclosed
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates BAYER MATERIALSCIENCE AG (DE) 2008-11-27 US disclosed
US-7250483-B2 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2007-07-31 US disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 US disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 US disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates HDHD5, ALKBH3, AHR GABRA1 4379/4885GABRB2 4342/4885CNR1 1022/4885
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES DHCR7, ADH1C, AKR1C4 GABRA1 3582/4885GABRB2 3216/4885CNR1 1181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.