Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22858647 | 0.83 | PLA2G4A (0.36) | TSHRHPGDHTTALDH1A1MAPT | |
| SCHEMBL19646306 | 0.83 | PLA2G4A (0.36) | TSHRHPGDHTTALDH1A1MAPT | |
| SCHEMBL23583870 | 0.81 | PLA2G4A (0.37) | TSHRHPGDHTTALDH1A1MAPT | |
| SCHEMBL21884187 | 0.79 | ALDH1A1 (0.32) | ALDH1A1PLA2G4A | |
| SCHEMBL20927061 | 0.78 | PLA2G4A (0.31) | PLA2G4A | |
| SCHEMBL18737542 | 0.78 | PLA2G4A (0.31) | PLA2G4A | |
| SCHEMBL24486553 | 0.76 | PLA2G4A (0.31) | PLA2G4A | |
| SCHEMBL19558827 | 0.75 | SMPD1 (0.32) | PLA2G4A | |
| SCHEMBL21720343 | 0.74 | ALDH1A1 (0.33) | TSHRHPGDHTTALDH1A1RAB9A | |
| SCHEMBL21720602 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277023-A1 | ANTIBIOTIC CONJUGATES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277023-A1 | ANTIBIOTIC CONJUGATES | DDOST, STT3B, DAD1 | TSHR 3335/4885HPGD 2099/4885HTT 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.