Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012302 | 0.82 | — | — | |
| SCHEMBL13292799 | 0.77 | — | — | |
| SCHEMBL8354695 | 0.72 | — | — | |
| SCHEMBL6120994 | 0.71 | GABRA1 (0.41) | — | |
| SCHEMBL14595269 | 0.71 | KAT2B (0.31) | KAT2BBAZ2B | |
| SCHEMBL9442 | 0.71 | CHRNB2 (0.42) | KAT2BBAZ2B | |
| SCHEMBL27621591 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL4621415 | 0.70 | CHRNB2 (0.41) | KAT2BBAZ2B | |
| SCHEMBL5472168 | 0.69 | — | — | |
| SCHEMBL23540869 | 0.69 | KMT2A (0.37) | KAT2BBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210276994-A1 | HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF | Guangzhou Yufan Nantu Biotechnologies Co., Ltd (CN) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276994-A1 | HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF | PGK1, HK1, PDXK | KAT2B 2413/4885BAZ2B 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.