Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | ACP1 | P24666 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940843 | 0.87 | SMN1; SMN2 (0.66) | ALDH1A1CYP3A4TSHRTDP1PDK1 | |
| SCHEMBL9798029 | 0.85 | DYRK1A (0.65) | ALDH1A1CYP3A4TSHRTDP1PDK1 | |
| SCHEMBL4939716 | 0.82 | DYRK1A (0.61) | ALDH1A1CYP3A4TSHRTDP1PDK1 | |
| SCHEMBL30916109 | 0.80 | CA1 (0.57) | ALDH1A1TDP1CA2SMN1; SMN2KMT2A | |
| SCHEMBL3080605 | 0.80 | CA1 (0.57) | ALDH1A1TDP1CA2SMN1; SMN2KMT2A | |
| SCHEMBL28930490 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1PDK1 | |
| SCHEMBL22130133 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1PDK1 | |
| SCHEMBL27566837 | 0.79 | DYRK1A (0.76) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| SCHEMBL2380048 | 0.79 | SMN1; SMN2 (0.59) | ALDH1A1CYP3A4TSHRTDP1PDK1 | |
| SCHEMBL334808 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | claimed |
| US-8586759-B2 | Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2013-11-19 | — | — | US | disclosed |
| US-8586759-B2 | Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | disclosed |
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) | 2011-09-15 | — | — | US | disclosed |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2011-09-01 | — | — | US | disclosed |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2011-09-01 | — | — | US | disclosed |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2011-09-01 | — | — | US | disclosed |
| US-4369324-A | Process for the preparation of 2-amino-6-nitrobenzothiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224442-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | HCCS, HLCS, GLUL | ALDH1A1 2394/4885CYP3A4 754/4885TSHR 3773/4885 |
| US-20110213124-A1 | METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS | HCCS, HLCS, GLUL | ALDH1A1 2394/4885CYP3A4 754/4885TSHR 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.