Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795106 | 1.00 | HPGDS (0.43) | HPGDSRAB9ANPC1CHRM4KMT2A | |
| SCHEMBL12068291 | 1.00 | HPGDS (0.43) | HPGDSRAB9ANPC1CHRM4KMT2A | |
| SCHEMBL21060598 | 0.89 | EPHX1 (0.39) | HPGDSRAB9ANPC1KMT2ATSHR | |
| SCHEMBL30103443 | 0.88 | EPHX1 (0.40) | HPGDSNAMPTPOLBEPHX1SCN9A | |
| SCHEMBL14752927 | 0.82 | — | — | |
| SCHEMBL12331013 | 0.82 | HPGDS (0.36) | HPGDSRAB9ANPC1CHRM4KMT2A | |
| SCHEMBL20331988 | 0.81 | BTK (0.51) | KMT2AEPHX1 | |
| SCHEMBL20960871 | 0.81 | BTK (0.51) | KMT2AEPHX1 | |
| SCHEMBL7642227 | 0.81 | NFKB1 (0.41) | HPGDSRAB9ANPC1CHRM4TSHR | |
| SCHEMBL12206722 | 0.81 | HSD11B1 (0.41) | HPGDSRAB9ANPC1CHRM4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046253-A1 | SODIUM CHANNEL REGULATOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-03-07 | — | — | WO | disclosed |
| EP-3877390-A1 | SPIRO-SULFONAMIDE DERIVATIVES AS INHIBITORS OF MYELOID CELL LEUKEMIA-1 (MCL-1) PROTEIN | Prelude Therapeutics, Incorporated (US) | 2021-09-15 | — | — | EP | disclosed |