Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900382 | 0.98 | CES2 (0.47) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL3876236 | 0.83 | CES2 (0.46) | CES2CES1DAORAB9ANPC1 | |
| Phenanthroline SCHEMBL16694068 | 0.83 | KDM4E (0.56) | RAB9ANPC1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL3268211 | 0.82 | CES2 (0.62) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL3997033 | 0.78 | CES2 (0.52) | CES2CES1DAORAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL27809835 | 0.76 | KMT2A (0.55) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL2915012 | 0.76 | RAB9A (0.54) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL6296917 | 0.76 | KMT2A (0.56) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL28213968 | 0.75 | — | — | |
| SCHEMBL1760911 | 0.75 | CES1 (0.58) | CES2CES1DAORAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012458-B2 | Rare-earth amidate coordination compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-06 | — | — | US | disclosed |
| US-20080306251-A1 | RARE-EARTH AMIDATE COORDINATION COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-12-11 | — | — | US | disclosed |
| US-20080306250-A1 | RARE-EARTH AMIDATE CHELATES | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-12-11 | — | — | US | disclosed |
| EP-1891019-A2 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006044732-A2 | 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| US-4550186-A | ANTITUMOR, ANTILIPEMIC, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | DUKE UNIVERSITY (US) | 1985-10-29 | — | — | US | disclosed |