Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268211 | 0.87 | CES2 (0.62) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL7837835 | 0.85 | RAB9A (0.51) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL6296917 | 0.80 | KMT2A (0.56) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL28808144 | 0.79 | — | — | |
| SCHEMBL7647867 | 0.79 | CES2 (0.62) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL31438886 | 0.78 | RAB9A (0.47) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL27691133 | 0.78 | KMT2A (0.47) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL16856706 | 0.77 | KMT2A (0.53) | RAB9ANPC1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL27375514 | 0.77 | HPGDS (0.61) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL27487815 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535276-B | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC | 2013-08-28 | — | — | CN | disclosed |
| EP-1438073-B1 | POLYOXYALKYLENE CONJUGATES AS ENZYME INHIBITORS | PROCTER & GAMBLE (US) | 2010-08-11 | — | — | EP | disclosed |
| CN-101535276-A | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-09-16 | — | — | CN | disclosed |
| EP-1438073-A2 | POLYOXYALKYLENES CONJUGATES AS ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2004-07-21 | — | — | EP | disclosed |
| CN-1511830-A | Compound used as antiphlogistic | ���ָ��.Ӣ��ķҩ�﹫˾ | 2004-07-14 | — | — | CN | disclosed |
| CN-1156452-C | Compounds as anti-inflammatory agents | ���ָ����Ӣ��ķҩ�﹫˾ | 2004-07-07 | — | — | CN | disclosed |
| US-6723788-B1 | Enzyme inhibitors | THE PROCTER & GAMBLE COMPANY | 2004-04-20 | — | — | US | disclosed |
| US-6541629-B1 | An enzyme inhibitor containing benzoxazine ring attached with 1-16 ethoxy groups used for treating diaper rash | THE PROCTER & GAMBLE COMPANY | 2003-04-01 | — | — | US | disclosed |
| EP-1212097-A2 | ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1212098-A2 | ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-12 | — | — | EP | disclosed |
| CN-1349509-A | Compounds as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMA (US) | 2002-05-15 | — | — | CN | disclosed |
| WO-2001017564-A2 | ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |
| WO-2001018181-A2 | ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |
| WO-2001017565-A2 | POLYOXYALKYLENES CONJUGATES AS ENZYME INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |