Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23797004 | 1.00 | GAA (0.39) | GAAEPHX2ALDH1A1NAMPTEPHX1 | |
| SCHEMBL24178194 | 0.86 | ACHE (0.43) | EPHX1KMT2A | |
| SCHEMBL24177671 | 0.86 | KDM4E (0.47) | ALDH1A1ADRA1AALOX15FAAHMEN1 | |
| SCHEMBL24177707 | 0.86 | PAOX (0.44) | ALOX15CYP1A2EGLN1GRIN2DGRIN3B | |
| SCHEMBL24178196 | 0.86 | KDM4E (0.47) | ALDH1A1ADRA1AALOX15FAAHMEN1 | |
| SCHEMBL23796909 | 0.86 | ACHE (0.43) | EPHX1KMT2A | |
| SCHEMBL23797006 | 0.84 | GAA (0.36) | GAAEPHX2ALDH1A1NAMPTEPHX1 | |
| SCHEMBL23797008 | 0.84 | GAA (0.36) | GAAEPHX2ALDH1A1NAMPTEPHX1 | |
| SCHEMBL17234488 | 0.81 | EGLN1 (0.40) | GAAALDH1A1ALOX15FAAHCYP1A2 | |
| SCHEMBL18528394 | 0.81 | EGLN1 (0.40) | GAAALDH1A1ALOX15FAAHCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877439-B1 | ANALGESIC AND ANTI-ADDICTIVE COMPOSITIONS FOR TREATMENT OF CHRONIC PAIN AND OPIOID ADDICTION | UNIV MINNESOTA (US) | 2026-03-11 | — | — | EP | claimed |
| US-12098118-B2 | Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-09-24 | — | — | US | claimed |
| US-20220002238-A1 | ANALGESIC AND ANTI-ADDICTIVE COMPOSITIONS FOR TREATMENT OF CHRONIC PAIN AND OPIOID ADDICTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-01-06 | — | — | US | claimed |
| EP-3877439-A2 | ANALGESIC AND ANTI-ADDICTIVE COMPOSITIONS FOR TREATMENT OF CHRONIC PAIN AND OPIOID ADDICTION | Regents of the University of Minnesota (US) | 2021-09-15 | — | — | EP | claimed |
| EP-3877439-B1 | ANALGESIC AND ANTI-ADDICTIVE COMPOSITIONS FOR TREATMENT OF CHRONIC PAIN AND OPIOID ADDICTION | UNIV MINNESOTA (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12098118-B2 | Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002238-A1 | ANALGESIC AND ANTI-ADDICTIVE COMPOSITIONS FOR TREATMENT OF CHRONIC PAIN AND OPIOID ADDICTION | OPRK1, OPRM1, OPRD1 | GAA 1332/4885EPHX2 2127/4885ALDH1A1 341/4885 |
| US-12098118-B2 | Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction | OPRK1, OPRM1, OPRD1 | GAA 1332/4885EPHX2 2127/4885ALDH1A1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.