Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19660155 | 0.86 | HDAC8 (0.50) | L3MBTL1KMT2ANPC1TDP1MAPT | |
| SCHEMBL22728863 | 0.81 | ALOX15 (0.47) | L3MBTL1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL22728769 | 0.80 | HDAC3 (0.44) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL19659999 | 0.80 | L3MBTL1 (0.60) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29041191 | 0.80 | KMT2A (0.72) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL19660209 | 0.77 | GSK3B (0.52) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29041217 | 0.75 | KMT2A (0.84) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9545966 | 0.75 | KMT2A (0.59) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL14312145 | 0.75 | GSK3B (0.50) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29041235 | 0.74 | KMT2A (0.62) | L3MBTL1KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464248-B1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | Bayer Pharma AG (DE) | 2021-09-08 | — | — | EP | disclosed |