Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2378665 | 0.99 | RAB9A (0.46) | RAB9AKMT2AMEN1OPRM1OPRL1 | |
| SCHEMBL2378997 | 0.92 | OPRL1 (0.51) | OPRM1OPRL1POLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL303067 | 0.91 | OPRL1 (0.52) | OPRM1OPRL1POLBALDH1A1HPGD | |
| SCHEMBL2378267 | 0.90 | OPRM1 (0.53) | RAB9AKMT2AMEN1OPRM1OPRL1 | |
| SCHEMBL2379624 | 0.89 | OPRL1 (0.54) | RAB9AKMT2AOPRM1OPRL1NPC1 | |
| Hydrochloric Acid SCHEMBL2379072 | 0.89 | OPRM1 (0.53) | RAB9AKMT2AMEN1OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL302160 | 0.88 | OPRL1 (0.53) | RAB9AKMT2AOPRM1OPRL1NPC1 | |
| SCHEMBL2379621 | 0.86 | OPRM1 (0.60) | KMT2AOPRM1OPRL1POLBPKM | |
| Hydrochloric Acid SCHEMBL302718 | 0.85 | OPRL1 (0.61) | KMT2AOPRM1OPRL1POLB | |
| SCHEMBL2379697 | 0.85 | OPRM1 (0.56) | KMT2AOPRM1OPRL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | claimed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | claimed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1751093-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110976-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129347-A1 | Cyclohexylacetic acid compounds | ACACA, HCAR2, PCCA | RAB9A 1391/4885KMT2A 2621/4885MEN1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.