Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23798667 | 0.86 | ACVR1 (0.36) | ACVR1EHMT2HTR7IP6K1HRH3 | |
| SCHEMBL23778276 | 0.86 | HRH3 (0.38) | OPRL1IP6K1HRH3KCNH2 | |
| SCHEMBL20066067 | 0.83 | MAPK1 (0.41) | HRH3 | |
| SCHEMBL23798608 | 0.79 | ACVR1 (0.35) | ACVR1IP6K1TLR9TLR7 | |
| SCHEMBL23799162 | 0.78 | FLT3 (0.42) | OPRL1HTR7HRH3OPRM1OPRK1 | |
| SCHEMBL23778372 | 0.78 | PRKCB (0.34) | OPRL1IP6K1 | |
| SCHEMBL23799149 | 0.76 | MAOA (0.41) | OPRL1ACVR1HRH3OPRM1OPRK1 | |
| SCHEMBL23798701 | 0.75 | OPRM1 (0.51) | OPRL1HTR7OPRM1OPRK1 | |
| SCHEMBL23798666 | 0.74 | CYP1A2 (0.39) | OPRL1HTR7OPRM1OPRD1OPRK1 | |
| SCHEMBL23798691 | 0.74 | OPRM1 (0.38) | OPRL1HTR7HRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526207-B1 | HETEROCYCLIC COMPOUNDS HAVING ACTIVITY AS MODULATORS OF MUSCARINIC M1 AND/OR M4 RECEPTORS IN THE TREATMENT OF CNS DISEASES AND PAINS. | HEPTARES THERAPEUTICS LTD (GB) | 2021-09-08 | — | — | EP | disclosed |