Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 9/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048024 | 0.76 | NPBWR1 (0.48) | NPBWR1MCHR1HSP90AA1UCHL1L3MBTL1 | |
| SCHEMBL2456576 | 0.71 | NPBWR1 (0.53) | NPBWR1MCHR1UCHL1 | |
| SCHEMBL29483303 | 0.70 | NPBWR1 (0.52) | NPBWR1MCHR1UCHL1L3MBTL1 | |
| SCHEMBL6603633 | 0.70 | NPBWR1 (0.52) | NPBWR1MCHR1UCHL1L3MBTL1HTT | |
| SCHEMBL4680080 | 0.68 | NPBWR1 (0.47) | NPBWR1MCHR1ERCC5FEN1UCHL1 | |
| SCHEMBL8886643 | 0.68 | NPBWR1 (0.51) | NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL2050022 | 0.68 | UCHL1 (0.57) | NPBWR1MCHR1UCHL1L3MBTL1ALDH1A1 | |
| SCHEMBL3319942 | 0.67 | NPBWR1 (0.47) | NPBWR1MCHR1UCHL1CYP2C19ALDH1A1 | |
| SCHEMBL20745582 | 0.66 | NPBWR1 (0.51) | NPBWR1MCHR1UCHL1ALDH1A1 | |
| SCHEMBL3320616 | 0.65 | NPBWR1 (0.45) | NPBWR1MCHR1UCHL1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178920-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |