Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050022 | 0.88 | UCHL1 (0.57) | NPBWR1MCHR1UCHL1KDM4EHTT | |
| SCHEMBL23013238 | 0.88 | TAS1R3 (0.52) | F2PLAUKLKB1ELANEKDM4E | |
| SCHEMBL2456576 | 0.87 | NPBWR1 (0.53) | NPBWR1MCHR1UCHL1 | |
| SCHEMBL29483303 | 0.86 | NPBWR1 (0.52) | NPBWR1MCHR1UCHL1ALOX15L3MBTL1 | |
| SCHEMBL1048024 | 0.84 | NPBWR1 (0.48) | NPBWR1MCHR1UCHL1HTTL3MBTL1 | |
| SCHEMBL8886643 | 0.82 | NPBWR1 (0.51) | NPBWR1MCHR1KDM4EALOX15 | |
| SCHEMBL4680080 | 0.80 | NPBWR1 (0.47) | NPBWR1MCHR1UCHL1 | |
| SCHEMBL14368129 | 0.80 | PTGER4 (0.59) | NPBWR1KDM4EALOX15L3MBTL1 | |
| SCHEMBL7056151 | 0.80 | F2 (0.48) | F2PLAUKLKB1ELANEHTT | |
| SCHEMBL13724241 | 0.79 | NPBWR1 (0.56) | NPBWR1MCHR1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181205-A | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-1156803-A4 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1156803-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6297233-B1 | Lactam inhibitors of FXa and method | BRISTOL-MYERS SQUIBB COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-2000047207-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-17 | — | — | WO | disclosed |