Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199877 | 0.80 | POLB (0.53) | HRH3F2RCHRNA4CHRNB2CHRNB4 | |
| SCHEMBL16027956 | 0.77 | — | — | |
| SCHEMBL17725298 | 0.76 | ACACB (0.43) | HRH3F2RCHRNA4CHRNB2CHRNB4 | |
| SCHEMBL23800755 | 0.75 | ITK (0.36) | ITKF2RCHRNA4CHRNB2CHRNB4 | |
| SCHEMBL7876851 | 0.73 | ACACB (0.40) | HRH3F2RCHRNA4CHRNB2CHRNB4 | |
| SCHEMBL11777365 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1LMNAL3MBTL1SMN1; SMN2PKM | |
| SCHEMBL23801253 | 0.72 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1SMN1; SMN2PKMMEN1 | |
| SCHEMBL25060914 | 0.71 | — | — | |
| SCHEMBL2413529 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29974433 | 0.69 | CHRNA4 (0.41) | F2RCHRNA4CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277061-A1 | YEATS INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277061-A1 | YEATS INHIBITORS AND METHODS OF USE THEREOF | YEATS2, YEATS4, MLLT1 | HRH3 2759/4885CHEK1 960/4885CHEK2 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.