SCHEMBL23799205

SCHEMBL23799205

O=C(O)c1cccn1OCCCC(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CACNA1B Q00975 2/20 0.32
PPARA Q07869 6/20 0.32
ALDH1A1 P00352 1/20 0.32
EPHX2 P34913 2/20 0.32
CYP2D6 P10635 2/20 0.32
PPARG P37231 1/20 0.32
KCNH2 Q12809 2/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23780589 0.80 TSHR (0.41) TDP1L3MBTL1ALDH1A1
SCHEMBL23798638 0.79 TSHR (0.43) TDP1ALDH1A1
SCHEMBL23798607 0.78 TSHR (0.45) TDP1ALDH1A1
SCHEMBL23798651 0.78 TSHR (0.45) TDP1ALDH1A1
SCHEMBL23798602 0.78 TSHR (0.45) TDP1ALDH1A1
SCHEMBL23797983 0.78 TSHR (0.45) TDP1ALDH1A1
SCHEMBL6832383 0.76 LMNA (0.40) POLBAPEX1TDP1L3MBTL1ALDH1A1
SCHEMBL23780602 0.73 L3MBTL1 (0.39) POLBAPEX1TDP1L3MBTL1ALDH1A1
SCHEMBL5510858 0.73 POLB (0.39) POLBAPEX1TDP1L3MBTL1ALDH1A1
SCHEMBL23780588 0.70 NR4A1 (0.45) MAOBPOLBAPEX1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-06-27 US disclosed
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2022-02-17 US disclosed
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-10-12 US disclosed
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2021-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048857-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI MAOB 229/4885POLB 2041/4885APEX1 3616/4885
US-11685716-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI MAOB 229/4885POLB 2041/4885APEX1 3616/4885
US-11142497-B2 Plant growth inhibiting agent, and plant growth inhibiting method using same ING2, CCNA1, CCNI MAOB 229/4885POLB 2041/4885APEX1 3616/4885
US-20210276950-A1 PLANT GROWTH INHIBITING AGENT, AND PLANT GROWTH INHIBITING METHOD USING SAME ING2, CCNA1, CCNI MAOB 229/4885POLB 2041/4885APEX1 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.