Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 9/20 | 0.34 |
| ▸ | TK2 | O00142 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384199 | 0.87 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL4135171 | 0.87 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL4592382 | 0.85 | TK2 (0.36) | TK1TK2 | |
| SCHEMBL4856132 | 0.78 | HSP90AA1 (0.38) | TK1 | |
| SCHEMBL1727535 | 0.77 | RNASE1 (0.40) | RNASE1TK1TK2 | |
| SCHEMBL8200498 | 0.76 | RNASE1 (0.40) | RNASE1TK1TK2 | |
| SCHEMBL8200495 | 0.76 | RNASE1 (0.40) | RNASE1TK1TK2 | |
| SCHEMBL8426742 | 0.76 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL7743997 | 0.75 | TK1 (0.37) | TK1TK2 | |
| SCHEMBL8370048 | 0.75 | RNASE1 (0.38) | RNASE1TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026348-B2 | Nucleoside derivative, modified oligonucleotide, method for their synthesis and applications thereof | LESNIKOWSKI ZBIGNIEW J | 2011-09-27 | — | — | US | disclosed |