SCHEMBL7743997

SCHEMBL7743997

Cc1cn([C@@]2(C(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@H](O)[C@@H](COP(N)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 9/20 0.37
TK2 O00142 7/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4384199 0.88 TK1 (0.38) TK1TK2
SCHEMBL4135171 0.88 TK1 (0.38) TK1TK2
SCHEMBL1727535 0.86 RNASE1 (0.40) TK1TK2
SCHEMBL8370048 0.83 RNASE1 (0.38) TK1TK2
SCHEMBL8426742 0.83 TK1 (0.38) TK1TK2
SCHEMBL1705935 0.83 RNASE1 (0.35) TK1TK2
SCHEMBL29834197 0.82 TK1 (0.36) TK1TK2
SCHEMBL7863893 0.81 RNASE1 (0.37) TK1TK2
SCHEMBL7640415 0.80 RNASE1 (0.38) TK1TK2
SCHEMBL1705943 0.80 TK1 (0.35) TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979233-A4 METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES PROLIGO L L C (US) 2001-03-21 EP disclosed
EP-0979233-A1 METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES NeXstar Pharmaceuticals, Inc. (US) 2000-02-16 EP disclosed
WO-1998047910-A1 METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES PROLIGO LLC (US) 1998-10-29 WO disclosed