SCHEMBL8200495

SCHEMBL8200495

Cc1cn([C@@]2(C(c3ccccc3)(c3ccccc3)c3ccccc3)CC(N)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.40
TK1 P04183 9/20 0.38
TK2 O00142 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8200498 1.00 RNASE1 (0.40) RNASE1TK1TK2
SCHEMBL1727535 0.89 RNASE1 (0.40) RNASE1TK1TK2
SCHEMBL7640415 0.83 RNASE1 (0.38) RNASE1TK1TK2
SCHEMBL8370048 0.83 RNASE1 (0.38) RNASE1TK1TK2
SCHEMBL29834215 0.81 RNASE1 (0.37) RNASE1TK1TK2
SCHEMBL29834214 0.81 RNASE1 (0.37) RNASE1TK1TK2
SCHEMBL7863893 0.81 RNASE1 (0.37) RNASE1TK1TK2
SCHEMBL9755145 0.80 RNASE1 (0.38) RNASE1TK1TK2
SCHEMBL1706305 0.80 RNASE1 (0.38) RNASE1TK1TK2
SCHEMBL7743997 0.80 TK1 (0.37) TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013785-A Polynucleoside chain having multiple ribonucleosides, the nucleosides coupled by guanidyl linkages THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-01-11 US disclosed