SCHEMBL23803941

SCHEMBL23803941

CCCC(=O)O[C@H]1C[C@@]2(C)[C@@H](CC[C@]2(O)C(=O)CS)[C@@H]2CCC3=CC(=O)CC[C@]3(C)[C@H]21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 12/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 2/20 0.60
POLB P06746 1/20 0.60
GAA P10253 1/20 0.60
HSD17B10 Q99714 4/20 0.59
NR3C2 P08235 4/20 0.59
NR3C1 P04150 3/20 0.59
PGR P06401 3/20 0.59
CYP2C19 P33261 3/20 0.59
SERPINA6 P08185 3/20 0.59
CYP3A4 P08684 3/20 0.59
NFKB1 P19838 2/20 0.59
SHBG P04278 2/20 0.59
KMT2A Q03164 2/20 0.59
LMNA P02545 3/20 0.57
AR P10275 1/20 0.57
CHRM1 P11229 1/20 0.57
PMP22 Q01453 2/20 0.56
TSHR P16473 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141827 0.92 HIF1A (0.70) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL141359 0.88 HIF1A (0.69) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL3488308 0.86 HIF1A (0.70) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL141850 0.86 HIF1A (0.70) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL110284 0.85 NR3C2 (0.69) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL146929 0.84 HIF1A (0.70) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL5488066 0.83 HIF1A (0.84) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL19327149 0.83 HIF1A (0.84) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL4983 0.83 HIF1A (0.84) HIF1ASMN1; SMN2MAPTPOLBGAA
SCHEMBL142560 0.83 HIF1A (0.66) HIF1ASMN1; SMN2MAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230019058-A1 METHOD FOR THE TREATMENT OF VIRAL INFECTIONS SOFTHALE NV (BE) 2023-01-19 US disclosed
EP-4117670-A1 METHOD FOR THE TREATMENT OF A RESPIRATORY DISEASE, DISORDER, OR CONDITION RESULTING FROM A VIRAL INFECTION Softhale NV (BE) 2023-01-18 EP disclosed
WO-2021180919-A1 METHOD FOR THE TREATMENT OF A RESPIRATORY DISEASE, DISORDER, OR CONDITION RESULTING FROM A VIRAL INFECTION SOFTHALE NV (BE) 2021-09-16 WO disclosed
CN-109789197-A For adjusting the composition and method of LAIR signal transduction 奈斯科尔公司 2019-05-21 CN disclosed
CN-107441480-A Polypeptide and its purposes as the medicine for treating multiple sclerosis, rheumatoid arthritis and other autoimmune disorders 卡姆普根有限公司 2017-12-08 CN disclosed
CN-103068399-A C1ORF32 for the treatment of multiple sclerosis, rheumatoid arthritis and other autoimmune disorders COMPUGEN LTD 2013-04-24 CN disclosed
CN-1130201-C Synergistic gold-containing compositions MEDICAL INNOVATIONS LTD (AU) 2003-12-10 CN disclosed
CN-1058150-C Topical aromatic releasing compositions RICHARD VICKS INC (US) 2000-11-08 CN disclosed
CN-1235550-A Synergistic gold-containing compositions MEDICAL INNOVATIONS LTD (AU) 1999-11-17 CN disclosed
CN-1079896-A The compositions of topical aromatic releasing RICHARDSON VICKS INC (US) 1993-12-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019058-A1 METHOD FOR THE TREATMENT OF VIRAL INFECTIONS IL5, TSLP, CRH HIF1A 2811/4885SMN1; SMN2 1116/4885MAPT 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.