Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 10/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383223 | 0.91 | RGS4 (0.32) | TNFPDE4AADORA2AADORA2BPDE4B | |
| SCHEMBL14150298 | 0.83 | TNF (0.33) | TNFPDE4AADORA2APDE4BPDE4C | |
| Urea SCHEMBL1901789 | 0.83 | PROKR1 (0.30) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL30238091 | 0.82 | ADORA2B (0.33) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL4126092 | 0.80 | APEX1 (0.40) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL9893563 | 0.80 | CYP1A2 (0.30) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL9723243 | 0.80 | CYP3A4 (0.48) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL10457248 | 0.80 | CYP3A4 (0.48) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL2500685 | 0.77 | ADORA2A (0.35) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL14150452 | 0.77 | TP53 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219641-A1 | AQUEOUS PRETREATMENT FOR BONDS WITH AN ENHANCED HEAT STABILITY | Sika Technology AG (CH) | 2023-08-02 | — | — | EP | disclosed |
| EP-3622029-B1 | AQUEOUS PRETREATMENT FOR BONDS WITH AN ENHANCED HEAT STABILITY | SIKA TECH AG (CH) | 2023-03-22 | — | — | EP | disclosed |
| US-8020719-B2 | Closure | SIKA TECHNOLOGY AG (CH) | 2011-09-20 | — | — | US | disclosed |
| US-20110223326-A1 | Means for applying and wiping away a liquid | SIKA TECHNOLOGY AG (CH) | 2011-09-15 | — | — | US | disclosed |
| US-20110052809-A1 | METHOD FOR APPLICATION OF AN ADHESION PROMOTER COMPOSITION TO A SUBSTRATE | SIKA TECHNOLOGY AG (CH) | 2011-03-03 | — | — | US | disclosed |
| US-20090305054-A1 | Means for applying and wiping away a liquid | SIKA TECHNOLOGY AG (CH) | 2009-12-10 | — | — | US | disclosed |
| US-20090246539-A1 | Thermally-Hardening Silicone Coating Suitable as Adhesive | SIKA TECHNOLOGY AG (CH) | 2009-10-01 | — | — | US | disclosed |
| US-20090101644-A1 | Closure | SIKA TECHNOLOGY AG (CH) | 2009-04-23 | — | — | US | disclosed |
| US-20090068477-A1 | Method for Applying an Adhesion Promoter Composition by Means of an Ultrasonic Atomizer | SIKA TECHNOLOGY AG (CH) | 2009-03-12 | — | — | US | disclosed |