SCHEMBL4126092

SCHEMBL4126092

CCO[Si](CCCn1c(=O)[nH]c(=O)n(CCC[Si](OCC)(OCC)OCC)c1=O)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.40
ADORA2B P29275 5/20 0.36
PDE4A P27815 4/20 0.36
ADORA2A P29274 4/20 0.36
PDE4B Q07343 4/20 0.36
PDE4C Q08493 4/20 0.36
PDE4D Q08499 4/20 0.36
ADORA3 P0DMS8 2/20 0.36
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 5/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 2/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
BRD4 O60885 1/20 0.32
BRD2 P25440 1/20 0.32
BRD3 Q15059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL383223 0.88 RGS4 (0.32) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL4129111 0.87 ADORA2B (0.36) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL4131368 0.83 APEX1 (0.42) APEX1ADORA2BPDE4AADORA2APDE4B
Urea SCHEMBL2380596 0.80 TNF (0.33) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL10457248 0.80 CYP3A4 (0.48) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL9723243 0.80 CYP3A4 (0.48) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL14150298 0.79 TNF (0.33) PDE4AADORA2APDE4BPDE4CPDE4D
SCHEMBL30238091 0.79 ADORA2B (0.33) ADORA2BPDE4AADORA2APDE4BPDE4C
SCHEMBL4117056 0.79 APEX1 (0.39) APEX1ADORA2BPDE4AADORA2APDE4B
SCHEMBL9893563 0.76 CYP1A2 (0.30) ADORA2BPDE4AADORA2APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023195294-A1 ADDITION-CURABLE LIQUID SILICONE RUBBER COMPOSITION FOR AIRBAGS, AND AIRBAG 信越化学工業株式会社 2023-10-12 WO disclosed
EP-2684690-B1 ADHESIVE-BONDED STRUCTURE COMPRISING BOTH ADHESIVE COMPOSITION AND WOOD MATERIAL KANEKA CORP (JP) 2018-02-21 EP disclosed
EP-2684690-A1 ADHESIVE-BONDED STRUCTURE COMPRISING BOTH ADHESIVE COMPOSITION AND WOOD MATERIAL Kaneka Corporation (JP) 2014-01-15 EP disclosed
EP-1418021-B1 Polishing pad JSR CORP (JP) 2009-01-21 EP disclosed
EP-1348747-B1 Gas barrier coating composition and method for manufacturing same JSR CORP (JP) 2007-02-14 EP disclosed
US-6992123-B2 Polishing pad JSR CORPORATION (JP) 2006-01-31 US disclosed
US-20040118051-A1 Polishing pad JSR CORPORATION (JP) 2004-06-24 US disclosed
EP-1418021-A1 Polishing pad JSR Corporation (JP) 2004-05-12 EP disclosed
US-20030187113-A1 Gas barrier coating composition and method for manufacturing same JSR CORPORATION (JP) 2003-10-02 US disclosed
EP-1348747-A1 Gas barrier coating composition and method for manufacturing same JSR Corporation (JP) 2003-10-01 EP disclosed