Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455490 | 0.89 | LMNA (0.54) | LMNAALDH1A1NPSR1RECQLMMP2 | |
| SCHEMBL3065763 | 0.89 | MMP2 (0.50) | LMNAALDH1A1NPSR1RECQLMMP2 | |
| SCHEMBL10076123 | 0.89 | MMP2 (0.50) | LMNAALDH1A1NPSR1RECQLMMP2 | |
| SCHEMBL5875639 | 0.86 | MMP2 (0.60) | MMP2ADAMTS5MMP9MMP1MMP13 | |
| SCHEMBL8839754 | 0.86 | MMP2 (0.60) | MMP2ADAMTS5MMP9MMP1MMP13 | |
| SCHEMBL2383878 | 0.82 | MMP2 (0.47) | LMNAALDH1A1NPSR1MMP2ADAMTS5 | |
| SCHEMBL8839327 | 0.82 | ALDH1A1 (0.50) | LMNAALDH1A1NPSR1MMP2ADAMTS5 | |
| SCHEMBL8839275 | 0.82 | ALDH1A1 (0.50) | LMNAALDH1A1NPSR1MMP2ADAMTS5 | |
| SCHEMBL8839537 | 0.82 | ALDH1A1 (0.50) | LMNAALDH1A1NPSR1MMP2ADAMTS5 | |
| SCHEMBL27430355 | 0.82 | MMP2 (0.53) | MMP2ADAMTS5MMP9MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022225-B2 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090131438-A1 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1798226-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131438-A1 | Triazole derivative | S1PR3, S1PR1, S1PR2 | LMNA 4808/4885ALDH1A1 2924/4885NPSR1 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.