Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.54 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455165 | 0.90 | ALDH1A1 (0.70) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL23818006 | 0.82 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL14963024 | 0.81 | RAB9A (0.46) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL23818000 | 0.80 | ALDH1A1 (0.72) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL14954833 | 0.79 | ALDH1A1 (0.45) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL10704334 | 0.78 | CETP (0.43) | ALDH1A1RAB9ASMN1; SMN2HTTMLYCD | |
| SCHEMBL14954772 | 0.77 | RAB9A (0.48) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL14955365 | 0.74 | POLQ (0.51) | ALDH1A1POLQTP53 | |
| SCHEMBL23818002 | 0.74 | ALDH1A1 (0.64) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL23818008 | 0.74 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | ALDH1A1 4563/4885RAB9A 1865/4885SMN1; SMN2 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.